All known Mega Drive games
1,223 games from Wikipedia, Wikidata, MobyGames and players' collections. Most are basic entries that list facts from public sources.
Games
- Spirou1995
- Spirou1996
- Splatterhouse
- Splatterhouse 21992
- Splatterhouse 31993
- Sports Talk Baseball1991
- Spot Goes To Hollywood1996
- Squirrel King1995
- SRD: Super Real Darwin1990
- Star Control1990
- Star Cruiser1990
- Star Trek: Deep Space Nine – Crossroads of Time1995
- Star Trek: Starfleet Academy – Starship Bridge Simulator1994
- Star Trek: The Next Generation1993
- Starblade1994
- Starflight1986
- Stargate1994
- Stargate1981
- Steel Empire1992
- Steel Talons1991
- Steven Seagal Is: The Final Option
- Stormlord1989
- Street Fighter II1991
- Street Fighter II Turbo1992
- Street Fighter II': Special Champion Edition1993
- Street Fighter II: Champion Edition1992
- Street Racer1996
- Street Racer1996
- Street Smart1991
- Streets of Rage1991
- Streets of Rage 21992
- Streets of Rage 31994
- Strider1989
- Strider1989
- Strider II1990
- Strike
- Striker1992
- Sub-Terrania1994
- Summer Challenge1993
- Sunset Riders1991
- Super Battleship1993
- Super Battletank1992
- Super Daisenryaku1989
- Super Donkey Kong 991998
- Super Fantasy Zone1992
- Super Hang-On1986
- Super High Impact1991
- Super Hydlide1987
- Super Kick Off1991
- Super Mario World
- Super Mario World 641997
- Super Monaco GP1990
- Super Skidmarks1995
- Super Smash TV1992
- Super Street Fighter II: The New Challengers1993
- Super Thunder Blade1988
- Super Volleyball1991
- Superman1987
- Superman1992
- Supreme Warrior1994
- Surgical Strike1993
- Surging Aura1995
- Switchblade1989
- Sword of Sodan1988
- Sword of Vermilion1989
- Sylvester and Tweety in Cagey Capers1994
- Syndicate1993
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